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About AMR | Fleming Fund

About AMR


What is Antimicrobial Resistance?

Antimicrobial resistance (AMR) is one of the world’s greatest threats. It’s caused by the overuse of medicines, such as antibiotics. But it is not just a health issue...

Why does AMR Matter?

AMR is an issue of great global concern. New estimates from the Global Burden of Bacterial Antimicrobial Resistance (GRAM) paper revealed that at least 1.27 million deaths per year were directly attributable to AMR. This means that AMR is a leading cause of death globally, higher than HIV/AIDs and Malaria.

Health economists estimate that, if current trends continue, AMR could result in over $100 trillion lost in economic activity and up to 10 million deaths each year by 2050. AMR affects all countries and resistance can spread across national borders and boundaries. We need to work together to fight the spread of resistance.

Find out more about the impacts of AMR in the GRAM paper.

How does AMR Spread?

AMR is evolution in action. It occurs naturally when microorganisms are exposed to antimicrobial drugs and adapt to survive the exposure. This can happen in humans, animals and the environment. Resistant microorganisms may then spread over time, becoming commonplace, meaning ordinary medicines are no longer effective.