‘AMR iceberg’ – the underlying social injustices of healthcare


The latest paper from the Fleming Fund Regional Grant team, GEAR up, argues that current action on AMR fails to adequately address the social and political determinants that create vulnerability and the (gendered) power relations sustaining inequity.

The study, published in Nature Communications, uses the ‘tip of an iceberg’ metaphor to illustrate a myriad of underlying issues and complex reasons why diagnostic services and antimicrobial treatment can be inaccessible.

Current research and policy frames AMR as a problem of antibiotic ‘misuse’, proposing solutions such as education and stronger regulation of the sale of antibiotics.

The GEAR up study challenges this approach, recommending a need to:

Creeping disaster

The study explains how AMR is a ‘creeping disaster’ that requires integrated, multisectoral, and cross-border action and can only be addressed at its root. Future research should address concerning evidence gaps related to inequities and injustices, informing access to antimicrobials and influencing the environmental transmission of resistance. These include refugee and humanitarian contexts and living in urban informal settlements.

AMR research requires attention to structural drivers, requires multi-sectoral action and a focus on accountability, particularly for these populations underserved by health systems. AMR interventions must also account for the intersections of human health, animal health and environmental health – exploring the imbalance of environmental and workplace settings and centring the voices of those most affected.

“We are grateful to the Fleming Fund for supporting a global focus on gender and equity in AMR. Through GEAR up, we conducted a systematic global literature review, which sought to unpack the underlying social and structural inequities driving AMR. Our conceptual framework uses the metaphor of an iceberg to highlight the equity biases within surveillance structures, significant gaps in the global evidence base and the missed opportunities to address the structural drivers of AMR.”

Senior author Dr Rosie Steege, GEAR up lead, LSTM.

GEAR up is a Fleming Fund Regional Grant, led by the Liverpool School of Tropical Medicine (LSTM), providing technical assistance and expertise related to mainstreaming Gender and Equity approaches across the Fleming Fund programme.

Listen to lead author Dr Katy Davis discussing the GEAR up paper.

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