The Lancet: Global, regional, and national sepsis incidence and mortality

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study published in The Lancet.

This paper highlights that despite decades of progress in healthcare, infectious diseases (the underlying causes of sepsis) remain a major cause of illness and death. The estimates provided in the paper are an important step in quantifying the impact of sepsis in low income countries. The Fleming Fund aims to improve surveillance capacity to generate primary data on the causes of sepsis, and especially the contribution of bacterial antimicrobial resistance. This is a critical step in improving the use of antibiotics so that their effectiveness is preserved for those who need them.

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The generation and sharing of antimicrobial resistance, use and consumption (AMR/U/C) data is invaluable for underpinning national and global AMR prevention and control strategies. However, these efforts are of limited use if such data and research findings are not simultaneously transformed into policy and practice actions.

Supported by a range of key stakeholders (including the Fleming Fund), the World Health Organization (WHO) recently published the [Third Progress Analysis]( of the Implementation of Antimicrobial Resistance National Action Plans (NAP-AMRs) in South-East Asia.